10 results
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
the dose of an ACEi ... Continue ACEi or ... evidence-based pharmacologic ... #Diabetes #CKD # ... #KDIGO #eGFR #Insulin
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
(stage IV or V CKD ... including most type 1 diabetics ... including most 2 diabetics ... Weight #Based #pharmacology ... endocrinology #diabetes
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... cells, triggering insulin ... contraindicated in CKD ... Sulfonylureas #Pharmacology ... #Summary #DM2 #diabetes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... Hyperkalemia: • CKD ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... Hyperkalemia: • CKD ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
patients with CKD ... , HF, or diabetes ... ACE inhibitors, ... #Hyperkalemia #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Medications: K+, ACEi ... transfusions), ↓insulin ... VBG (acidosis), CK ... Treatments: • Insulin
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
Pheochromocytoma - Diagnosis ... sedimentation rate, insulin ... leukocytosis, psychiatric ... carbohydrate metabolism (insulin ... apparent type 2 diabetes
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Insulin dependent ... ACEi/ARBs - Hold ... Diabetes regimen ... stratification #diagnosis
Medications Contributing to Dysgeusia

Antimicrobial medicines	Macrolides, fluoroquinolones, ampicillin, metronidazole, tetracycline, trimethoprim-sulfamethoxazole, amphotericin B, terbinafine and other antimycotic
Angiotensin-converting enzyme (ACE ... anti-depressants Psychiatric ... #Differential #Diagnosis ... #Pharmacology