9 results
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Management of Diabetes ... patients with Type 1 diabetes ... or Type 2 diabetes ... #Diabetes #CKD # ... #Insulin #metformin
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
(stage IV or V CKD ... including most type 1 diabetics ... including most 2 diabetics ... Weight #Based #pharmacology ... endocrinology #diabetes
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... Insulin Lifestyle ... Improved outcomes in CKD ... EricsMedicalLectures/featured #diabetes
Diabetic Myonecrosis (Diabetic Muscle Infarction)
 • Spontaneous ischemic necrosis of skeletal muscle (anterior thigh or calf)
Diabetic Myonecrosis ... (Diabetic Muscle ... • Suspect in diabetic ... Common pattern: ↑CK ... #management #diabetes
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Summary Mechanisms ... cells, triggering insulin ... contraindicated in CKD ... diabetes #endocrinology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
produce endogenous insulin ... ketoacidosis (AKA ... • Diabetic ketoacidosis ... #differential #diagnosis ... #management #endocrinology
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
Summary 10 percent ... sedimentation rate, insulin ... leukocytosis, psychiatric ... carbohydrate metabolism (insulin ... apparent type 2 diabetes
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
patients with psychiatric ... - Co-morbid diabetes ... Differential Diagnosis ... : Diabetes Insipidus ... #management #nephrology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Insulin dependent ... ASA class If ... Diabetes regimen ... medical and surgical management ... stratification #diagnosis