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Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Hepatocellular Injury: • AST ... to liver than AST ... bilirubin: ↑ • AST ... hematoma) • AST
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Enzymes (LFTs) - Causes ... Liver Injury • AST ... /ALT elevation > ... Alk phos • ALT ... • R value = (ALT
Etiology of Acute Liver Failure – bolded entities are most likely to cause AST/ALT in the
most likely to cause ... AST/ALT in the
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... CPK 5X ULN • AST ... /ALT Elevation 4 ... :1 ratio (AST declines ... Diagnosis #Management #causes
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
out additional causes ... evaluation for other causes ... If other causes ... ALT, alanine aminotransferase ... ; AST, aspartate
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... Nucleotidase • ALT ... & AST normal or ... on but elevated as
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Hyperglycemia - ↑ AST ... /ALT • Treatment ... hyperthyroidism #causes
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Chemistry Tests - AST ... , ALT, Alkaline ... Bilirubin Metabolism AST ... and ALT: • AST ... liver, 80% of AST
Rhabdomyolysis - Differential Diagnosis Framework Rhabdomyolysis = Destruction of skeletal muscle with leakage of contents into circulation.
myoglobin, aldolase, AST ... /ALT, LDH). ... Differential #Diagnosis #Causes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Hepatocellular Level • AST ... to liver than AST ... elevated ALP • AST ... NT: ↑ • ALP > AST ... • Near normal AST
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