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diagnosis management differential causes cardiology clinical treatment gastroenterology pocus nephrology peds pulmonary workup ddxof hematology criticalcare em neurology pediatrics pharmacology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Chemistry Tests - AST ... , ALT, Alkaline ... Bilirubin Metabolism AST ... and ALT: • AST ... liver, 80% of AST
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Differential Diagnosis Algorithm ... or AST > ALP): ... • Severe - ALT ... or AST): • US ... Transaminitis #Algorithm
Gestational Hypertension & Preeclampsia Gestational Hypertension (gHTN) • BP > 140/90 • Onset > 20 wks gestation
Thrombocytopenia • Elevated AST ... /ALT • Pulmonary ... Thrombocytopenia • Elevated AST ... /ALT • Hemolysis ... #Preeclampsia #Classification
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Hepatocellular Level • AST ... to liver than AST ... elevated ALP • AST ... NT: ↑ • ALP > AST ... • Near normal AST
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... to liver than AST ... elevated ALP • AST ... NT: ↑ - ALP > AST ... differential #diagnosis #algorithm
Standardized Physical Abuse Guideline <6 months of age • Social work consult • Skeletal survey • Head
survey • Head CT, AST ... , ALT, lipase ... Abdominal CT if AST ... months of age if AST ... or ALT> 80, signs
Features of Components of Liver Function Tests #Diagnosis #IM #GI #LFTs #Liver #Function #Tests #Locations #AlkPhos
Locations #AlkPhos #AST ... #ALT #Ddxof
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
aminotransferase (AST ... aminotransferase (ALT
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Injury • AST ... /ALT elevation > ... Alk phos • ALT ... • R value = (ALT ... + ULN ALT) / (alkaline
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
disproportionate increase in AST ... /ALT compared with ... compared with AST ... /ALT) Hepatocellular ... Diagnosis #hepatology #algorithm
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