14 results
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... : • Mast cell-mediated ... in > 90% of cases ... is key • Mast ... #Classification
Causes of Angioedema: Differential Diagnosis Framework
Mast-cell mediated:
 • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
Causes of Angioedema ... IgE dependent allergic ... deficiency (hereditary angioedema ... Infections • CCV #Angioedema ... #allergy
There are 2 Major Types of Angioedema:
 - Mast cell / histamine mediated – usually presents
Major Types of Angioedema ... : - Mast cell / ... AND allergic symptoms ... presents WITHOUT allergic ... #Classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antibodies bind to mast ... When the specific allergen ... degranulation of mast ... Hypersensitivity #Types #Classification ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... reactions #types #allergy ... #table #classification
Some H1 antihistaminic Drugs in Clinical Use
1st Generation Antihistamines:
Ethanolamjnes - Carbinoxamine (Clistin), Dimenhydrinate (salt of diphenhydramine)(Dramamine),
Clinical Use 1st ... Fexofenadine (Allegra ... antihistamines #classification ... #Pharmacology #classes
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
allergens and activate mast ... leading to an allergic ... cell surfaces causes ... causes development ... #Types #Classification
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
pass system: 1st ... Anaphylaxis • Angioedema ... pass = Primary Causes ... : • Mast cell ... Diagnosis #hematology #allergy
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
functional status - Able ... metabolic equivalent able ... ASA class If ... event, follow ACC algorithm ... Stable patients
American Society of Anesthesiologists (ASA) Classification
The ASA classification (Table) aims to predict perioperative mortality rates but
) Classification ... The ASA classification ... (Table) aims to ... Higher ASA class ... #Classes #Classification