8 results
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Involvement, Spares ... , Sicca Syndrome ... Disease, Rheumatoid Vasculitis ... RA #diagnosis #rheumatology ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... Aseptic necrosis of hip ... Demyelinating syndromes ... valve lesions Abdominal ... erythematosus #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tracts Immune Complex ... - GI tract: abdominal ... purpura: strong sign ... Supply gut -> abdominal ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... causing endothelial injury ... Hyperviscosity Syndrome ... HBV infection, HIV ... classification #rheumatology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
adhesion of IgA complexes ... 85%) - Colicky abdominal ... nephrotic/nephritic syndrome ... and ankles) #HSP ... Pathophysiology #Diagnosis #Signs
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... clinical context and signs ... Glomerulonephritis / Vasculits ... hepatitis serology, HIV ... renal biopsy • Abdominal
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... of shoulder and hip ... pauci-immune GN Immune Complex ... gut involvement, abdominal ... Differential #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... to local skin injury ... • Nonsurgical abdominal ... diagnosis #management #signs ... #symptoms #rheumatology