18 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
, Normal PT (INR ... , Normal PT (INR ... #INR #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Diagnosis Algorithm ... reticulocyte count, LFTs ... iron studies, PT ... /aPTT Differential ... #hematology #workup
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal • ... #Algorithm #hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Plasma → Recheck abnormal ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... PT and the aPTT ... amyloidosis #Abnormal ... #PT #aPTT #Prolonged ... hematology #coagulation
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... #differential # ... hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... #Diagnosis #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... selected cases: INR/PT ... , aPTT(liver disease ... gastric bypass), LFT ... #Workup #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... mild cases) • PT ... hemophilia type (e.g ... Management #treatment #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
platelet, PT, PTT ... 1 or Type 3) — differentiate ... Platelet #disorders #hematology ... #hemepath #differential ... #diagnosis #Aggregometry