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differential management hepatitis algorithm lfts rheumatology cirrhosis syndrome autoimmune causes chronic hepatopulmonary oncology transaminitis treatment workup aclf acute afib ah
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... Wilsons, Pregnancy - AFLP ... LFTs #Elevated #Abnormal ... #hepatology #LiverFunctionTests
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Drugs • AIH ... • Cholestatic disease ... Others #LFTs #Hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... of Pregnancy (AFLP ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... - If both are normal ... function may be abnormal ... #differential #diagnosis ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... • Near normal ... disease: > 2 ... #chemistry #diagnosis ... #differential #Hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Defects, Drugs, Liver ... Disease, PNH ... Blood Smear ↑ abnormal ... #hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... bleeding disorder Clinical ... bruising • Skin ... VonWillebrand #Disease ... #Diagnosis #Hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... disease, liver ... Alcohol-Associated Hepatitis (AAH ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... ALP, alkaline phosphatase ... disease; AST, aspartate ... disease; T2DM, ... #Algorithm #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... Examination: • Skin ... obstruction • ALP ... or higher • Liver ... #workup #hepatology
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