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differential hematology causes aptt pt bleeding bruising acutekidneyinjury aki chemistry child dic disorders disseminated hemostasis hepatitis inr interpretation intravascular laboratory
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... #Coagulation #Abnormal ... APTT #Laboratory #Hematology ... #Diagnosis #Workup
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PT (INR), Normal ... PTT, Normal PT ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... #Causes #diagnosis ... #differential #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
- Differential Diagnosis ... Algorithm Thrombocytopenia ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... function may be abnormal ... #algorithm #hepatology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... amyloidosis #Abnormal ... #Causes #diagnosis ... #coagulation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
- If both are normal ... • Albumin • Coagulation ... of ALP • Near normal ... #chemistry #diagnosis ... #differential #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... DIC • Severe Liver ... - APTT < 1.5 x normal ... #diagnosis #causes ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... the PT remains prolonged ... #Differential #Diagnosis ... #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
Non-accidental Injury ... splenomegaly, abnormal ... neurology, back ... #Limping #NWB #Algorithm ... Peds #Pediatrics #Diagnosis
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