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differential management algorithm acute causes hematology gastroenterology lfts nephrology transaminitis aclf aflp aih aki anemia aplastic ascites autoimmune bilirubin chemistry
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... #Patterns #Liver ... #Injury #hepatology ... #differential #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... obstruction, HELLP Syndrome ... #Diagnosis #Causes ... Acute #algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Injury (DILI) ... Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... vein: Budd-chiari syndrome ... #injury #hepatitis ... #algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... non-essential drug/HDS treatments ... • Autoimmune hepatitis ... #Injury #Diagnosis ... #Algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential #Hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... injury (INR > 2 ... mg/dL) or acute liver ... failure #HepatitisB ... Indications #management #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... injury, though ... upper limit of normal ... regarding need for treatment ... #Management #Hepatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential Diagnosis ... investigations abnormal ... cryoglobulins, hepatitis ... Acute #Kidney #Injury
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Hepatic imaging: Normal ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #differential #diagnosis
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