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hematology differential algorithm aptt bleeding blood bruising gastroenterology product prolonged pt reactions treatment workup abscess aih amyloid amyloidosis autoimmune biliary
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... deficiency in the common ... • Reduced liver ... amyloidosis #Abnormal ... #hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... inhibitors to the common ... #diagnosis #differential ... #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Treat primary cause ... #diagnosis #causes ... #treatment #management ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... defects in the common ... discern these causes ... #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... disease US — Normal ... Bile Ducts • Common ... Others #LFTs #Hepatology ... #Algorithm #Causes
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... arthralgias) are common ... upper limit of normal ... Muscle Abs (ASMA) (common ... #Management #Hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
regarding the diagnosis ... <45% and SF is normal ... If other causes ... hemochromatosis #algorithm #diagnosis ... #management #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Female:Male 9:1 • Common ... intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... or higher • Liver ... #workup #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... and M panel Management ... levels are within normal ... DDX - Other causes ... #diagnosis #management
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