6 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Diagnosis Algorithm ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Causes #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... inhibitor of a coagulation ... intravascular coagulation ... #Diagnosis #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... - APTT < 1.5 x normal ... #diagnosis #causes ... #treatment #management ... #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- If both are normal ... • Albumin • Coagulation ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... amyloidosis #Abnormal ... #differential # ... hematology #coagulation