10 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... or higher • Liver ... malignancies, Hepatic ... #cholangitis #diagnosis ... #workup #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... elevation DDX of Hepatic ... Primary biliary Cholangitis ... (PBC) - Other ... #Algorithm #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
intra- and extra-hepatic ... asymptomatic at diagnosis ... disease management ... #diagnosis #management ... #summary #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Injury: • Hepatic ... Autoimmune hepatitis, PBC ... function may be abnormal ... #algorithm #hepatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... Initial labs: CBC ... hemoglobin/hemosiderin, Hepatic ... #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- If both are normal ... replaced by non-hepatic ... of ALP • Near normal ... #chemistry #diagnosis ... #differential #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... 100mg/dL) - Heparin ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... reported (eg AIH-PBC ... upper limit of normal ... #Management #Hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
regarding the diagnosis ... <45% and SF is normal ... hemochromatosis; HIC, hepatic ... hemochromatosis #algorithm #diagnosis ... #management #hepatology
Pyogenic liver abscess in children
Common bacterial causes in children:
 • S.aureus
 • Strep spp
 • Enteric
from contiguous focus ... Biliary tree (cholangitis ... through: - Hepatic ... #differential #diagnosis ... #hepatology