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differential hematology signs algorithm management oncology apml biliary bilirubin caudaequina cecs cholangitis chronicexertional cirrhosis comparison compartmentsyndrome congenital differentiation disorders enzymes
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... suspicious clinical symptoms ... presence of metabolic syndrome ... Areas of diagnostic ... #Algorithm #Hepatology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... spine Signs / Symptoms ... Areflexia (loss of normal ... #MSK #pathophysiology ... #diagnosis #symptoms
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... PBC Signs and Symptoms ... or higher • Liver ... #workup #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... Amy Chung, MD, MSc ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #Hematology #Diagnosis
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... anterior/posterior MSK ... heart (2-5%), liver ... (pain/abnormal
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
the spleen or liver ... translocation • Types: Classification ... also arise in normal ... Differential Diagnosis ... #differential #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of about 30% of normal ... of hemolysis or liver ... examination; nonspecific symptoms ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... 500 mg QD until normal ... #management #hematology
Chronic Exertional Compartment Syndrome (CECS) • Diagnosis Of CECS requires patient to undergo the same exertional
Exertional Compartment Syndrome ... (CECS) • Diagnosis ... > 20 mmHg • Normal ... CompartmentSyndrome #CECS #pathophysiology ... #symptoms #msk
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