15 results
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
hyperbilirubinemia syndrome ... of about 30% of normal ... of hemolysis or liver ... examination; nonspecific symptoms ... #hepatology #diagnosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
fold elevation, Bilirubin ... necrosis HELLP Syndrome ... fold elevation, Bilirubin ... Disease #Pregnancy #hepatology ... #differential #diagnosis
Posterior Ankle Impingement (Os Trigonum) Syndrome - MSK Radiology
Imaging Findings:
 • Os trigonum which has marrow
(Os Trigonum) Syndrome ... - MSK Radiology ... flexion but no symptoms ... #clinical #Radiology ... #diagnosis #msk
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... function may be abnormal ... • Gilbert's syndrome ... #algorithm #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Blood Smear ↑ abnormal ... - Unconjugated Bilirubin ... #hematology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
and unconjugated bilirubin ... and excretion of bilirubin ... the hepatorenal syndrome ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... Resonance Imaging (MRI ... #POCUS #radiology ... #differential #diagnosis ... table #appearance #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
week • Direct bilirubin ... Elevation: • Bilirubin ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential #Hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... suspicious clinical symptoms ... presence of metabolic syndrome ... Areas of diagnostic ... #Algorithm #Hepatology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Areflexia (loss of normal ... suspected, immediate MRI ... #MSK #pathophysiology ... #diagnosis #symptoms