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diagnosis clinical hematology blood bloodsmear differential causes microscopy management auer auerrods disorders endocrinology hemolytic macrocytic macrocytosis oncology rods thrombocytopenia workup
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... promyelocytic leukemia (APL ... peripheral blood smear ... #Clinical #Path ... BloodSmear #Blood #Smear
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 Elliptocyte - Note the shape of these appropriately named erythrocytes. In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... #Clinical #Path ... BloodSmear #Blood #Smear
Dacrocytes (tear drop cells) Other poikilocytes resemble a pear or teardrop. The narrow, tapered end may be
metaplasia, pernicious anemia ... some hemolytic anemias ... #Clinical #Path ... BloodSmear #Blood #Smear
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Differential Diagnosis Algorithm ... Signs of anemia ... Abnormal peripheral smear ... Differential #Diagnosis #Algorithm
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
peripheral blood smear ... iron deficiency anemia ... #Clinical #Path ... PeripheralBloodSmear #BloodSmear #Anemia
Auer Rods - Bone marrow aspiration revealed 5% blasts and 65% promyelocytes; many promyelocytes had prominent
#Clinical #Path ... #APL #AuerRods # ... AcutePromyelocyticLeukemia #Smear
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
myelogenous leukemia (AML ... #Clinical #Path ... BloodSmear #Blood #Smear ... Rods #AuerRods #AML
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... peripheral blood smear ... Pruritis after hot bath ... - infiltrates (anemia ... • Peripheral smear
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Differential Diagnosis Algorithm ... Normochromic RBCs on Smear ... Spherocytes on Smear ... Differential #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Peripheral blood smear ... → Sickle Cell anemia ... Differential #Diagnosis #Algorithm
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