7174 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... Secondary Cold Agglutinin ... Viral Infection Clinical ... or fingers • Acrocyanosis
Summary Table of Causes of Acrocyanosis:

Dr. Ann Marie Kumfer @AnnKumfer

#Acrocyanosis #Differential #Causes #Diagnosis #Causes #Table
Table of Causes of Acrocyanosis ... @AnnKumfer #Acrocyanosis
perioral cyanosis- A blue color around the lips and philtrum is a relatively common finding shortly
This is part of acrocyanosis ... #clinical #photo ... perioral #cyanosis #acrocyanosis
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
hemoglobinuria) • Cold Agglutinin
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
cryoglobulinemia, Cold agglutinin ... dermatology #skin #clinical
Common Raynaud's Mimickers
 - Acrocyanosis
 - Chill blains (pernio)
 - Erythromelalgia
 - Frostbite
 - Achenbach's Syndrome

Dr.
Mimickers - Acrocyanosis
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
macroglobulinemia, cold agglutinin ... #Clinical #Path
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
( +/- ) Cold agglutinin
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
macroglobulinemia, cold agglutinin ... #Clinical #Path
Causes of Cyanosis in the Newborn - Differential Diagnosis Algorithm
Peripheral Only:
 • Poor Perfusion
 • Acrocyanosis
Hemoglobinopathy:
Perfusion • Acrocyanosis