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Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... : • Classic Acromegaly ... resistance pseudo-acromegaly ... or refractory cases ... thakre_anuj) #Acromegaly
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... GH excess prior ... plate fusion -> acromegaly ... • Other rare causes ... of acromegaly include
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... growth hormone (GH ... #Acromegaly #Signs
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... - Giantism or acromegaly ... GrowthHormone #GH
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Puberty Onset • GH ... Resistance • Acromegaly ... endocrinology #causes
Causes of Pulmonary Fibrosis

#Pulmonary #Fibrosis #Causes #Differential #Diagnosis
Causes of Pulmonary ... Fibrosis #Pulmonary ... #Fibrosis #Causes
Hirsutism - Differential Diagnosis
Defined as excessive dark, coarse, male-pattern hair growth
Hirsutism causes in premenopausal women:
 •
growth Hirsutism causes ... Cushing's Syndrome, Acromegaly ... tumors Hirsutism causes ... Cushing's Syndrome, Acromegaly
Causes of Cough and Hemoptysis
Acute Inflammation 
 - Laryngitis 
 - Tracheobronchitis 
 - Mycoplasma and
Causes of Cough ... Bronchiectasis - Pulmonary ... Mitral Stenosis - Pulmonary ... , Chemicals, Gases ... #Differential #Causes
Diffuse consolidation
The most common cause of diffuse consolidation is pulmonary edema due to heart failure.
This is
The most common cause ... consolidation is pulmonary ... from the various causes ... redistribution of pulmonary ... a superimposed pulmonay
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Causes of Proximal ... Endocrinopathies - Acromegaly ... #differential #causes