118 results
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... growth hormone (GH ... #Acromegaly #Signs
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... GH excess prior ... plate fusion -> acromegaly ... rare causes of acromegaly ... Overproduction #diagnosis #signs
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... : • Classic Acromegaly ... Pseudoacromegaly/Acromegaloid ... resistance pseudo-acromegaly ... thakre_anuj) #Acromegaly
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... abn lipid • GH ... - Giantism or acromegaly
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
spinal cord - Signs ... Ataxia (early sign ... weakness (late sign ... dexterity loss (early signs ... #symptoms #msk
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
test • + Tinel sign ... • + Froment's sign ... + Wartenbergs sign ... pathophysiology #signs ... #symptoms #msk
Flexor Tenosynovitis (FTS)

The clinical diagnosis of FTS is made using Kanavel’s Signs:
 - Fusiform swelling.
 -
using Kanavel’s Signs ... Kanavels #Criteria #Sign ... #Hand #MSK #Diagnosis
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... • Spurling's sign ... pain Lasegue's sign ... Radiculopathy #MSK ... #diagnosis #signs
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Puberty Onset • GH ... Resistance • Acromegaly
Common Signs in Parkinson's Disease - SMART Mnemonic

Shuffling-Gait 
Mask-like Face 
Akinesia 
Rigidity 
Tremor 

#SMART #Mnemonic #Parkinsons
Common Signs in ... Shuffling-Gait Mask-like ... Mnemonic #Parkinsons #Signs