304 results
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... growth hormone (GH ... #Acromegaly #Signs
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... GH excess prior ... plate fusion -> acromegaly ... rare causes of acromegaly ... Overproduction #diagnosis #signs
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... : • Classic Acromegaly ... Pseudoacromegaly/Acromegaloid ... resistance pseudo-acromegaly ... thakre_anuj) #Acromegaly
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... abn lipid • GH ... - Giantism or acromegaly
Corrigan's Sign in Severe Aortic Regurgitation

- Dr. Andres S. Kohan https://twitter.com/KohanAndres

#Corrigans #AorticRegurgitation #Pulse #PhysicalExam #Video #Neck
Corrigan's Sign ... #PhysicalExam #Video ... #Neck #Signs #
Brudzinski's Sign in Meningitis

Forced flexion of the neck elicits a reflex flexion of the hips. It
Brudzinski's Sign ... #Brudzinskis #Signs ... PhysicalExam #Clinical #Video
Muller's sign in Aortic Regurgitation - Systolic pulsations of the uvula 

In chronic severe aortic regurgitation,
Muller's sign in ... variety of physical signs ... Müller's sign is ... #Mullers #sign # ... uvula #clinical #video
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Puberty Onset • GH ... Resistance • Acromegaly
Chvostek's Sign - Physical Exam - Hypocalcemia

Chvostek's sign is described as the twitching of facial muscles
Chvostek's Sign ... Hypocalcemia Chvostek's sign ... Chvostek's sign ... #Chvosteks #Signs ... #Hypocalcemia #Video
Positive Hoffmann's sign (finger flexor reflex) in a patient with Multiple Sclerosis

The Hoffmann's reflex test itself
Positive Hoffmann's sign ... are not useful signs ... to cerebellar signs ... Abnormal #Clinical #Video ... #Signs #PhysicalExam