29 results
Action potential in cardiomyocytes
The action potential in typical cardiomyocytes is composed of 5 phases (0-4), beginning
phase Phase 0: Depolarization ... Phase 1: Early repolarization ... phase Phase 3: Repolarization ... Pathophysiology #Cardiac #ActionPotential ... #Repolarization
Action Potential: Depolarization and repolarization of a neuron

#ActionPotential #Depolarization #Repolarization #Neuron #Neurology #Pathophysiology
Action Potential: Depolarization ... and repolarization ... of a neuron #ActionPotential ... #Depolarization ... #Repolarization
Major electrocardiogram findings induced by left ventricular hypertrophy (LVH)
An increase in left ventricular mass augments the
widening of the QRS ... duration and leftward QRS ... alteration in repolarization ... in left atrial depolarization
Approach to ECGs
Check
 - Age, gender, name
 - 25mm/s; 10mm/mV
 - 1mm = 40ms; 0.1 mV
Rate
- RR only - #QRS ... 2 dots = 3s; #QRS ... (1) Pfor every QRS ... ectopic atrial pacemaker ... rsr'), V-pacemaker
ECG characteristics of early repolarization
 - The ST segment elevations are concave and most pronounced in
characteristics of early repolarization ... hallmark of early repolarization ... is the end-QRS ... - The end-QRS ... EKG #ECG #Early #Repolarization
Modified Sgarbossa Criteria - Diagnostic Checklist for diagnosing MI in LBBB or Pacemaker
1) Identify LBBB or
MI in LBBB or Pacemaker ... Identify LBBB or Pacemaker ... LBBB: QRS >120ms ... axis deviation Pacemaker ... - Fusion: odd QRS
Class I Antiarrhythmics and their Key Pharmacologic Properties

Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer")
Class IB
for the rapid depolarization ... • Slows depolarization ... results in wide QRS ... involved in phase 3 repolarization ... • Prolongs repolarization
Differential Diagnosis for ST Segment Elevations
 - ACUTE STEMI 
 - PULMONARY EMBOLISM 
 - LBBB
EMBOLISM - LBBB (PACEMAKER ... - BENIGN EARLY REPOLARIZATION
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens repolarization ... 6.0 mEq/L, rapid repolarization ... waves disappear, QRS ... to 10.0 mEq/L, QRS ... classic sine wave (QRS-T
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Blockade • Slows depolarization ... cells • Widens QRS ... Blockade • Slows depolarization ... Blockade • Slows depolarization