7792 results
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
ß-glucocerebrosidase activity ... in GBA1 gene Clinical ... Disease #Diagnosis #Signs
Pulmonary Embolism on POCUS Echocardiogram

Mid 30's female with chest pain/dyspnea.  Triage EKG (no prior).
Activate cath lab ... RV, McConnell's sign ... Echocardiogram #A4c #clinical ... cardiology #McConnells #sign
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... Excessive glutamate activity ... cellular function Clinical ... Exam: clinical evidence ... by decreasing activity
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathogenesis and clinical ... Poliomyelitis Activity ... causes #symptoms #signs
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
Pathogenesis and Clinical ... any occupational activity ... engage in any new activity ... Embarrassment prevents new activity ... Psychiatry #Criteria #Signs
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
knees, shoulders Signs ... sx improve with activity ... Ultrasound Diagnosis: CLINICAL
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
pathogenesis and clinical ... pyrophosphatase activity ... CPPD #Disease #Signs
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
BZD) withdrawal: clinical ... Incr Sympathetic Activity ... pathophysiology #diagnosis #signs
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Diagnosis: HLH signs ... absent NK cell activity
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Diagnosis and Clinical ... circulating cortisol 2. activity ... mineralocorticoid activity ... Hypercortisolism #Diagnosis #signs