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diagnosis differential injury causes transaminitis albumin chemistry dili druginduced gradient interpretation liverenzymes patterns rvalue serum
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Normal Peritoneum ... Cirrhosis - Alcoholic ... hepatitis ... fibrosis - Acute ... #differential #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... - Acute Viral Hepatitis ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) ... Cirrhosis - Alcoholic ... hepatitis - Cardiac ... Veno-occlusive disease - Acute ... Differential #Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... disease US — Normal ... hepatitis • Drugs ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... viral hepatitis ... ALT Ratios: • Alcoholic ... #differential #Hepatology ... transaminitis #LFTs
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute ... disorder (e.g. ascites ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... function may be abnormal ... ALT Ratios: • Alcoholic ... #hepatology
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