15 results
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... hepatitis • Drugs ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... 100-500): • NAFLD ... • Cirrhosis ... Chronic Viral Hepatitis ... #Diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... HSV • Toxic: Alcohol ... Antitrypsin • Other: NAFLD ... Causes #Acute #algorithm ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Inflammatory • Alcoholic ... Primary Biliary Cirrhosis ... #Causes #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Congenital, Others, Cirrhosis ... #diagnosis #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... cirrhosis, Portal ... #Patterns #Liver ... #Injury #hepatology ... transaminitis #differential
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Inflammation - Hepatitis ... Sarcoidosis Toxic - Alcohol ... Nonalcoholic fatty liver ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... antitrypsin • Other: NAFLD ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Non-Alcoholic Fatty Liver Disease (NAFLD) - Diagnosis Algorithm
Low Suspicion:
    ≤ 1 feature of
Non-Alcoholic Fatty ... Liver Disease ( ... NAFLD) - Diagnosis ... Algorithm Low ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
ALT Ratios: • Alcoholic ... : < 1 • Cirrhosis ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis