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diagnosis differential injury lfts acute causes chronic transaminitis aclf chemistry druginduced failure gastroenterology hepatitisb hepatocellular interpretation liverenzymes rvalue treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... , HBV, HCV, HEV, ... EBV, CMV), Alcohol-related ... #Diagnosis #Algorithm ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Algorithm • ... viremia or have cirrhosis ... HAV immunity; Liver ... #HBV #Algorithm ... #Treatment #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Alcohol • ... hepatitis • Drugs ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... Injury (DILI) ... Viral Hepatitis ... #Hepatology #gastroenterology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
: Alcohol, Medication ... Antitrypsin • Other: NAFLD ... Medication, Pregnancy, Alcoholic ... Causes #Acute #algorithm ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... ALT Ratios: • Alcoholic ... : < 1 • Cirrhosis ... differential #diagnosis #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... antitrypsin • Other: NAFLD ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... serologies, HCV ... ALT Ratios: • Alcoholic ... : < 1 • Cirrhosis ... #differential #Hepatology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... HCV, DILI, HCC, ... #Hepatitis #Management ... #Algorithm #hepatology
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