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differential causes injury lfts transaminitis management acute albumin chronic gradient nephrology treatment abnormal aclf chemistry criteria dili disease druginduced elevated
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
Diagnosis of ascites ... ≤ 2.5 g/dL: Cirrhosis ... syndrome, Massive liver ... #gradient #hepatology ... #algorithm
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... - Cirrhosis ... - Alcoholic hepatitis ... #Causes #diagnosis ... #differential #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) ... - Differential Diagnosis ... - Alcoholic hepatitis ... - Massive liver ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Algorithm Malignant ... Non-Malignant • Fatty Liver ... Inflammatory • Alcoholic ... Primary Biliary Cirrhosis ... #Hepatology
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... Diagnosis Chronic ... liver disease ( ... hepatitis) - 80% ... #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... cirrhosis, Portal ... #Patterns #Liver ... #Injury #hepatology ... #differential #diagnosis
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... of portal HTN: ascites ... (SAAG>I.I), esophageal ... /acute hepatitis ... #causes #hepatology
Approach to the Hospitalized Patient with Cirrhosis 1) Recognize and Manage Decompensation • Ascites • Variceal Bleeding
Decompensation • Ascites ... Common Scenarios • Alcoholic ... Hepatitis • Hepatorenal ... Portosystemic Shunt • Liver ... #diagnosis #treatment
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Algorithm Severe ... hepatitis • Drugs ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... Sarcoidosis Toxic - Alcohol ... Nonalcoholic fatty liver ... 14 percent) #Diagnosis ... #Differential #Hepatology
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