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diagnosis differential management injury ascites lfts chronic cirrhosis gastroenterology saag transaminitis abdominalpain acidosis aclf aflp aih albumin autoimmune bariatric bypass
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... months without treatment ... Infections Alcohol-Associated ... #Hepatology #gastroenterology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... HSV • Toxic: Alcohol ... Medication, Pregnancy, Alcoholic ... #Acute #algorithm ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... • Right Heart Failure ... Inflammatory • Alcoholic ... #Causes #Hepatology
Right Upper Quadrant Pain Liver: - Infectious: Acute viral hepatitis, Liver abscess - Non-infectious: hepatitis (Alcohol, Medications),
Quadrant Pain Liver ... viral hepatitis ... (Alcohol, Medications ... congestion (e.g. heart failure ... differential #diagnosis #causes
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... can be bridge to Liver ... #Algorithm #treatment ... #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Sarcoidosis Toxic - Alcohol ... Nonalcoholic fatty liver ... Congestive heart failure ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • NAFLD • Alcohol ... hepatitis • Drugs ... Others #LFTs #Hepatology ... #Causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute ... #hepatology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Supportive with treatment ... liver failure ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
failure 1) Hepatocellular ... Drugs (MDMA), Alcohol ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
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