527 results
Remitting Seronegative Symmetrical Synovitis

Pitting tenosynovitis. Pink hands also. Hint: pink hands may not be related to
Remitting Seronegative ... Janetbirdope #Remitting ... Pitting #Edema #clinical
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... anti-GBM) 10%: - Low Complement ... Vasculitis - Normal Complement ... Kumfer @AnnKumfer #Pulmonary
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... With associated pulmonary
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
Pathogenesis and Clinical ... infections • Clinical ... is rare Normal complement ... response: The complement ... cell membranes -> Critical
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... dead tissue • Complement ... activation of complement
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
Admitting in the ... NOTES: The last clinic ... the Pt's current clinical ... depending on the clinical ... @EmmGeezee #Admitting
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... activation • Complement ... tagged with C3 complement ... - Activate Complement ... : Abs activate complement
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm
INDICATIONS FOR TESTING:
 • Recurrent angioedema (without urticaria)
 •
Complement 1 esterase ... abdominal pain and vomitting ... ARUPLabs #C1INH #Complement
Atypical HUS - Hemolytic Uremic Syndrome
Unlike typical HUS, which is shigatoxin mediated, aHUS is not typically
It is complement ... renal, cardiac, pulmonary ... with Eculizumab (complement
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Early and Late Clinical ... joints - Remitting