12 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Patterns Nuclear ... • Reticular/AMA ... PBC/SjS OS - AMA ... ARUPConsult @ARUPLabs #ANA ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(ANA) ANA or Anti-NucIear ... 33% of healthy adults ... context of other symptoms ... : The ANA patterns ... #patterns #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... Testing - Nuclear ... ARUPConsult @ARUPLabs #ANA ... #Antinuclear #Antibody ... #diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
- Symptoms of ... hepatocellular pattern ... though cholestatic pattern ... Autoantibodies: Auto-Nuclear ... ANA) & Anti-Smooth
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... the chest/trunk Symptoms ... ANA Labs: • ↑ESR ... #rheumatology # ... management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
< 30 years - Aorta ... • GCA: - Aorta ... Presentation - Systemic Symptoms ... LFT • ESR • ANA ... #rheumatology #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Epidemiology: • Young adults ... meningitis), MCC CNS symptoms ... Glucocorticoids 5-ASA ... #management #signs ... #symptoms #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Pathophysiology remains unclear ... Neurological symptoms ... Imaging Patterns ... circulation: MCA ACA ... #management #neurology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... those coming off aorta ... them, but urgent rheumatology ... Temporal #Signs #Symptoms ... #Diagnosis #Management