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management differential lupus druginduced signs symptoms syndrome vasculitis aortitis classification comparison dil disease erythematosus gca giantcell polychondritis relapsing sjogrens summary
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... polychondritis, Behcet's ... (RA), Systemic ... erythematosus (SLE ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Oral aphthae : SLE ... : SLE, Reactive ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Workup: - ANA ... life-threatening • Treatment ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Discontinuation of causal ... months to years) Systemic ... comparison #table #rheumatology ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... < 30 years - Aorta ... VASCULITIS: • Behçet ... vasculitis, and SLE ... #rheumatology #
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... identifies 85 to 95% of cases ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... ): • Aorta and ... tract, and often causes ... vasculitis • Behcet ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Arthralgia and Arthritis ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... is rare in DIL, SCLE-DIL ... Workup: - ANA ... DrugInduced #Lupus #DIL #rheumatology ... #diagnosis #treatment
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Large vessels (aorta ... such as: • SLE ... Sarcoidosis • Behcet ... affected tissue Treatment ... Polychondritis #rheumatology
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