16 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... Liver biopsies show ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Conjunctivitis, Mucositis, Rash ... , Cough • +/-Nausea ... Polymorphous rash ... KD #vasculitis #rheumatology ... #management #treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
with urticarial rash ... /splenomegaly, liver ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... by a hemophilia treatment ... Avoid meds that ... #Management #treatment ... #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Discontinuation of causal ... Manifestations: Malar rash ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Cutaneous larva migrans skin Rash
25 F recent Caribbean vacation, walked barefoot on sand and now with
. diagnosis? ... Adult hookworms live ... self-limited Diagnosis ... No treatment is ... larva #migrans #skinRash
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... eruptions, diarrhea, liver ... #Transfusion #diagnosis ... #management #hematology