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differential hepatology acute algorithm blood management product reactions rheumatology vasculitis abscess acidosis aki arterial bilirubin chemistry children congenital cryoglobulinemia cryoglobulins
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
- Classification ... ) • Liver failure ... tubular necrosis (causes ... : sepsis, meds, ... #diagnosis #nephrology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Diagnosis Hepatocellular ... obstruction, HELLP Syndrome ... #Diagnosis #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... • Gilbert's syndrome
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
injury < 26 weeks ... disease: > 2 • NASH ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential #Hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... or renal injury ... - Compartment syndrome ... Injury: • Reduced ... #typeb #classification
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... • Nephrotic Syndrome ... , Ischemic Liver ... Vasculitis • Injury ... pathophysiology #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
causing endothelial injury ... • They can cause ... Cryoglobulins Cause ... #types #classification ... #rheumatology #
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of hemolysis or liver ... injury ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Pyogenic liver abscess ... Common bacterial causes ... pediatrics #children #peds ... #differential #diagnosis ... #hepatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... mucositis - Rash ... #rheumatology # ... classification
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