20 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Increased red cell ... Hemolysis #Hemolytic #Anemia ... Differential #Causes #Workup ... #Hematology #Diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... Phosphorus CLL ... ) CLL Symptoms: ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... Diagnosis: • ... • Neutropenia, anemia ... Lymphocytic #Leukemia #diagnosis ... #workup #oncology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
RBC = red blood cell ... serum level for all ... of the initial work-up ... #Diagnosis #Macrocytosis ... Homocysteine #Algorithm #Workup
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma Diagnosis ... hypercalcemia) • Anemia ... plus one of: • Anemia ... plasma clonal cell ... #Management #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... 10,000 new cases diagnosed ... cytopenias (usually anemia ... Allogeneic stem cell ... treatment #hematology #oncology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... Red cell distribution ... #Algorithm #Diagnosis ... #Workup #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... minimal tumor burden Diagnosis ... 5) Symptoms of anemia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... marrow plasma cell ... diseases, CML, ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Consider sickle cell ... #Differential #Diagnosis ... #Algorithm #workup