9 results
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
available lab test ... interruption per treatment ... table ... and procedural bleeding ... with a very low bleeding
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... thereby leading ... metabolization leading ... #Interactions #Table
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... at high risk of bleeding ... interactions and bleeding ... DOAC, direct oral ... #DOAC #VTE #Malignancy
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... #management #algorithm ... #pharmacology #treatment ... #medications #table
ED Treatment of 
Abnormal Uterine Bleeding 

Hemodynamically unstable 
Resuscitation 
 • ABCs! 
 • Fluids +
ED Treatment of ... Abnormal Uterine Bleeding ... coagulopathy Pregnancy test ... Hemodynamically stable ... Abnormal #Uterine #Bleeding
Comparison of Fever Algorithms for Infants <3 months old

AGE, INCLUSION, TESTS 
REQUIRED, "LOW RISK" CRITERIA, TREATMENT,
Comparison of Fever Algorithms ... AGE, INCLUSION, TESTS ... RISK" CRITERIA, TREATMENT ... #EBM #Fever #Algorithm ... #Comparison #Table
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
& Dry) is the treatment ... causing hypovolemia needing ... & Dry” is the treatment ... #differential #algorithm ... #table #foamed
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Avoid Warfarin and DOAC ... during Delivery • Stable ... Period • Breast-feeding ... management #cardiology #treatment
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
metabolic equivalent able ... event, follow ACC algorithm ... determine if stress test ... Stable patients ... - what is the bleeding