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Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... Initial exposure to allergen
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... cell surfaces causes ... leading to an allergic ... causes development ... An allergic reaction
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
hypereosinophilia (HE) Caused ... cytokines Common causes ... infection - Allergic ... disease Rare causes ... + T cells) - Allergic
NAACP mnemonic for the major causes of Eosinophilia N = Neoplasia (CML, Hodgkins lymphoma) A =
for the major causes ... lymphoma) A = Allergy ... #Differential #Causes
Causes of Angioedema: Differential Diagnosis Framework Mast-cell mediated: • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
Causes of Angioedema ... IgE dependent allergic ... Differential #Diagnosis #Causes ... #allergy
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Causes of Urticaria ... Aeroallergens - Contact allergen ... mediated - Contact allergen ... Mediated #NonIgE #Causes
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 Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Acne • Allergy ... Diagnosis #Algorithm #Causes
Assessment of the Child with Chronic Asthma Are there other allergic disorders? - Allergic rhinitis - Eczema,
Are there other allergic ... - Allergic rhinitis ... Other causes should ... triggers: - Allergic
Assessment of the Child with Eczema Distribution of atopic eczema - The distribution of eczema tends to
Causes of exacerbation ... Ingestion of an allergen ... an irritant or allergen ... - What causes exacerbation ... Problems from other allergic
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