637 results
Drugs that Cause Fever
Most commonly:
Amphotericin B, Antihistamines, Asparaginase, Barbiturates, Bleomycin sulfate, Methyldopa, Penicillins, Phenytoin sodium, Procainamide,
Drugs that Cause Fever ... Occasionally: Allopurinol ... hydrochloride #Drug #Fever
Causes of Fever: IMADE Mnemonic
INFECTION
 • Infection 1.0 - Common & Localizing: Base Rate
 • Infection
Causes of Fever: ... carcinomas present with fever ... aminopenicillins. allopurinol ... NSAlDs • DIHS: allopurinol ... with DVT/PE + fever
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... irritation, rash, fever ... the kidney #Allopurinol
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Cough, Dyspnea, Fever ... propylthiouracil, allopurinol
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
12-24 Hours • Fever ... Hyperuricemia: Allopurinol ... intolerant of allopurinol ... combined with allopurinol
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... prophylaxis with allopurinol
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
acute rheumatic fever ... remember yellow and allopurinol
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Muscle swelling - Fever ... Allopurinol for
Faget Sign - Pulse-Temperature Dissociation
Causes of Relative Bradycardia
 • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... Mountain spotted fever ... , Drug fever
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - ... Continuous Fever ... (Step ladder: fever ... Intermittent Fever ... or no fever