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rheumatology management lupus differential systemic activation ana antinuclear centralretinalartery classification comparison crao druginduced eularacr hematology macrophage mas muscle myelitis myopathy
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Lupus Erythematosus ... Clinical and Immunologic ... Criteria CLINICAL ... - NON-SCARRING ALOPECIA
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Clinical Domains ... : Non-scarring alopecia ... Highly specific antibodies ... #SLE #Systemic ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... and permanent alopecia ... Differential Diagnosis ... • Nonscarring alopecia ... Induced Lupus: • Symptoms
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... context of other symptoms ... likely it will be clinically ... #rheumatology #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... Systemic Lupus Erythematosus ... Photosensitivity, Alopecia ... #rheumatology #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
develops on the background ... Fever is the main clinical ... [SLE], AOSD) • ... Histopathologic criteria ... Activation #Syndrome #Diagnosis
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... systemic lupus erythematosus ... (SLE), polymyositis ... myopathy (IMNM) → Antibodies ... IU/I • SAMS clinical
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... GCA, SLE, GPA) - ... prominent within a background ... #diagnosis #signs ... #symptoms
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Criteria: • Sensory ... Bilateral signs and/or symptoms ... Disorders: - SLE ... Antiamphiphysin antibodies
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... and fatigue Criteria ... cases such as: • SLE ... Anti-Matrilin-1 Ab ○ Antibodies
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