9 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... 40, F:M 9:1 • Clinical ... Photosensitivity, Alopecia ... life-threatening • Treatment ... Usual therapeutic management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... Photosensitivity, Alopecia ... life-threatening • Treatment ... Usual therapeutic management
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
Overview of antifungal ... tolerable • Limited clinical ... #valleyfever #management ... #treatment #antifungals ... comparison #table #pharmacology
Antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis
Fluconazole
 - Benefits: Low cost/tolerable
Antifungal agents ... effects in the treatment ... Weaknesses: Limited clinical ... Coccidioidomycosis #pharmacology ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
develops on the background ... Fever is the main clinical ... erythematosus [SLE ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Rheumatology #Diagnosis #Management
Majocchi’s Granuloma due to Trichophyton rubrum 
This is GMS stain and culture of a skin biopsy
Treatment: Itraconazole ... recommended as sole ... Rx: Oral antifungal ... recommended Mayo Clinic ... #photo #microscopy
IDSA Recommendations for Preventing and Treating Cryptococcosis in HIV-AIDS
Treatment for cryptococcosis consists of 3 phases: induction,
Cryptococcosis in HIV-AIDS Treatment ... as substantial clinical ... least 1 year (AI)—see ... #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
 •
weeks or until clinically ... interactions with ARV (see ... IDSA #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology