1325 results
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Non-Malignant • Amyloidosis ... Algorithm #Causes #Hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
deposition disease, and amyloidosis ... diseases, CML, amyloidosis ... MGUS #diagnosis #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... sub-types based on the hematologic ... multiple myeloma, AL amyloidosis ... myeloma and AL amyloidosis ... #Significance #hematology
CHINA Mnemonic for Causes of Splenomegaly

C - Congestion (portal hypertension)
H - Hematologic (sickle cell, hemolytic anemia)
I
hypertension) H - Hematologic ... Autoimmune (RA, amyloidosis
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
macroglobulinemia, primary amyloidosis ... Electrophoresis #SPEP #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
with systemic amyloidosis ... #differential #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Dermal Vessels: - Amyloidosis ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Fibrillar deposits: • Amyloidosis ... CVS+joints) • Amyloidosis ... Paraproteinemias #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
with systemic amyloidosis ... #differential #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
or factor X • Amyloidosis-associated ... Vasculitis • Amyloidosis ... Differential #Diagnosis #Hematology