38 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... Cold Agglutinin Syndrome ... Clinical Presentation ... younger pts) Differential ... #hematology #diagnosis
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Weakness • Cardio-pulmonary ... diseaseAnemia ... • Chronic Infection ... Lambert-Eaton Myasthenic Syndrome
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Hematologic • Anemia ... • Malignancy Infectious ... Obstructive Pulmonary ... Disease Neurologic ... Fatigue Syndrome
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... neuropathy (LHON) plus MRI ... lesions and clinical ... noninflammatory #differential ... #diagnosis
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... - HIV infection ... hemolytic anemia ... #Differential # ... Causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... pylori test (GI symptoms ... anti-phospholipid antibodies ... changes), high MCV anemia ... #Diagnosis #Causes
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Autoimmunity • Chronic ... autoimmune hemolytic anemia ... DDX - Other causes ... syndrome, HIV)
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation causes ... inflammation Symptoms ... • Mounier-Kuhn syndrome ... #differential # ... diagnosis
Causes of Intrauterine Growth Restriction / Small for Gestational Age - Differential Diagnosis Algorithm
Fetal Factors:
 -
Factors: - TORCH Infections ... • Turner syndrome ... Hypoxemia • Pulmonary ... diseases ... • Chronic anemia