12 results
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... specifically: iron deficiency ... #Differential #
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Reactive: • Anemia ... blood loss (Fe deficiency ... Diagnosis #causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... malignancy • Iron deficiency ... anemia #Thrombocytosis ... #Differential #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hematology for workup ... Acute hemolysis, deficiency ... anemia, Rebound ... #Platelets #Differential
Causes of Wide Pulse Pressure - Differential Diagnosis
Physiologic:
 • Advanced age-arteriosclerosis (less compliant arteries)
 • Well
Causes of Wide Pulse ... Pressure - Differential ... - Severe iron deficiency ... anemia (reduced ... #cardiology
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
and Differential ... Metabolism Severe Anemia ... #Differential # ... Diagnosis #cardiology ... #causes
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Whipple, vitamin deficiency ... Alzheimer - 1st cause ... Dementia - 2nd cause ... MNCD #Dementia #Differential ... #Diagnosis #Geriatrics
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... • Severe iron deficiency ... anemia (reduced ... #Diagnosis #Pathophysiology ... #causes #cardiology
Quincke's Pulse in a patient with a normal echocardiogram (non-valvular)

A 70 y/o man presents with new
Workup for cause ... point thiamine deficiency ... highest on my differential ... deficiency via ... Fingernails #Nailbed #Cardiology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... or folic acid deficiency ... treatments • Copper deficiency ... Workup: • Complete ... blood count with differential