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Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... #Clinical #Path ... BloodSmear #Blood #Smear
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... #Clinical #Path ... BloodSmear #Blood #Smear
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
peripheral blood smear ... iron deficiency anemia ... #Clinical #Path ... PeripheralBloodSmear #BloodSmear #Anemia
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
with hemolytic anemias ... #Clinical #Path ... BloodSmear #Blood #Smear
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
This smear was from ... and hemolytic anemias ... #Clinical #Path ... BloodSmear #Blood #Smear
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
peripheral blood smears ... in sickle cell anemia ... . pernicious anemia ... #Clinical #Path ... BloodSmear #Blood #Smear
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
seen in hemolytic anemias ... microangiopathic hemolytic anemia ... #Clinical #Path ... BloodSmear #Blood #Smear
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... peripheral blood smear ... #Clinical #Path ... BloodSmear #Blood #Smear
Sickle cells
These photos show sickle cells on peripheral blood smears. In the left photo target cells
peripheral blood smears ... no significant anemia ... #Clinical #Path ... BloodSmear #Blood #Smear
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Abnormal peripheral smear ... Autoimmune Hemolytic Anemias ... #Hemolytic #Anemias