13 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... autoantibodies that will cause ... (for secondary APS ... #SLE #CNS #neurology ... #rheumatology #
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Systemic Lupus Erythematosus ... Clinical Domains ... least 2 joints • Neurologic ... #diagnosis #rheumatology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease (MS ... Motor Nerves: ALS ... #differential #diagnosis ... #neurology
Hoffman's sign. Even in this specific case, accompanied by a clonus outline (rhythmic contractions). The median
this specific case ... both as an afferent ... middle finger. 2) Ask ... Positive #Abnormal #clinical ... #video #neurology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
with edema • Erythematous ... violaceous macules and erythematous ... auricular papules Clinical ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
thiazidic, PPI, ACE ... Discontinuation of causal ... Systemic Lupus Erythematosus ... comparison #table #rheumatology ... #diagnosis #management
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
the follow up video ... presentation is known as ... the hospital, diagnosed ... with MS, and started ... #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Generalized fatigue - ALS ... myasthenia Diagnosis ... immunologic assay - MuSK ... Myasthenia #Gravis #diagnosis ... #management #neurology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... (to support a diagnosis ... ANA and RF (if clinical ... #testing #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
affects the skin, neurologic ... ischemia • Skin: Erythematous ... node syndrome • Coronary ... tract, and often causes ... #Rheumatology