26 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... Type of Liver Injury ... #Medications #Differential ... LiverInjury #Hepatology #Pharmacology ... #Causes #DILI
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Drug-induced Liver Injury ... dose dependent injury ... Idiosyncratic #differential ... #Diagnosis #Management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... • Iatrogenic: DILI ... Unconjugated Bili ... > 90% of Total Bili ... #hepatitis #differential
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... (>1000): • DILI ... Drug-induced liver injury ... #Tests #LFTs #Differential
Amiodarone-Induced Lung Iniurv (AILI) - Timeline
Hours to days (peri-procedurally): ARDS
Days to months: DAH
Weeks: Eosinophilic pneumonia
Weeks to
Amiodarone-Induced Lung Iniurv ... (AILI) - Timeline ... Induced #LungIniurv #AILI ... pulmonary #diagnosis #differential
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Drug-Induced Liver Injury ... (DILI) Viral Hepatitis ... Procedures Management ... gastroenterology #management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... syndrome, Electrical injury ... Rhabdomyolysis #Differential ... #Diagnosis #Management
Thoracic Trauma - Lethal 6 and Hidden 6 of Thoracic Trauma
The Lethal 6 of Thoracic Trauma:
• Esophageal Injury ... Blunt Cardiac Injury ... Blunt Thoracic Injury ... Trauma #diagnosis #management ... #injuries #differential
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... - Differential ... urinalysis, labs - Management ... Acute #Kidney #Injury ... #AKI #Differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
ALF): • Liver injury ... hepatocellular injury ... Unconjugated Bili ... > 90% of Total Bili ... chemistry #diagnosis #differential