19 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... • Immunologic Workup ... Evolution: Chronic disease ... Erythematosus #Diagnosis ... #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hematologic: Acute blood ... Vasculitides, IBD, Celiac disease ... #Algorithm #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... plateletcount), peripheral blood ... ), HBsAg/anti-HBc ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Algorithm Normal Blood ... Low Serum B12 - Anti-IF ... Low Serum B12 - Anti-IF ... Algorithm #Causes #Hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... • Autoimmune diseases ... Adult-onset Still disease ... #management #treatment ... #summary #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Coombs testing for anti-C3d ... and negative anti-lgG ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... hemolytic #anemia #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... screening for disease ... with established disease ... Avoid meds that ... #hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
ANTI-MDA5 DERMATOMYOSITIS ... onset [33-74%] • Blood ... severity of the disease ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... mononeuritis multiplex WORKUP ... reveals increasing blood ... #management #treatment