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Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... 40, F:M 9:1 • Clinical ... ANA > - Anti-ENA ... Usual therapeutic management ... Erythematosus #Diagnosis #Management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... ) - Anti-ENA ... 40, F:M 9:1 • Clinical ... Usual therapeutic management ... rheumatology #diagnosis #management
Central Retinal Vein Occlusion (CRVO) Clinical: • Sudden, painless, monocular loss of vision • "Blood and
Occlusion (CRVO) Clinical ... fundoscoplc exam Management ... Ophthalmology consult • Anti-vascular ... CRVO #Diagnosis #Clinical
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Thrombocytopenic Purpura Clinical ... Intracranial hemorrhage Management ... Corticosteroids • IVIG or anti-D
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
Diagnosis, causes and management ... cryoglobulinemia vasculitis Clinical ... - Specific anti-infectious ... the absence of anti-infectious ... Cryoglobulinemic #Diagnosis #Management
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis Clinical ... Highly variable clinical ... & Anti-ALC Abs ... Hepatitis (eg Viral) Management ... AIH #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... chemotherapy, anti-CD20 ... manifestations, Anti-IFN-y ... Lymphohistiocytosis #diagnosis #management
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
rheumatoid factor) • anti-CCP ... Ultrasound Diagnosis: CLINICAL ... • Biologics: Anti-TNF ... Arthritis #diagnosis #management
Myocarditis 5 Principles of Myocarditis: 1. Build clinical suspicion 2. Decide on EMBx 3. Manage acute cardiac injury 4. Manage chronic
Build clinical suspicion ... myocarditis Clinical ... calcineurin inhibitor, anti-metabolite ... Myocarditis #diagnosis #management
Allergic Bronchopulmonary Aspergillosis (ABPA) WHAT IS IT? Hypersensitivity response to Aspergillus fumigatus in the airways • Primarily affects
WHAT ARE THE CLINICAL ... corticosteroids +/- anti-fungal ... voriconazole) • Anti-lgE ... pulmonary #diagnosis #management
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