8247 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... ) - Anti-ENA ... constitutional symptoms • Treatment ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... ANA > - Anti-ENA ... to 30% - Anti-dsDNA ... 60% - pANCA anti-MPO ... life-threatening • Treatment
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
cryoglobulinemia vasculitis Clinical ... neuropathy Treatment ... - Specific anti-infectious ... the absence of anti-infectious
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Unknown cause Treatment ... chemotherapy, anti-CD20 ... diagnosis #management #treatment
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis Clinical ... Highly variable clinical ... ) (common, and Anti-LKM ... & Anti-ALC Abs ... regarding need for treatment
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... ) - Anti-ENA ... ) - Anti-histone ... constitutional symptoms • Treatment ... rheumatology #diagnosis #treatment
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
rheumatoid factor) • anti-CCP ... Ultrasound Diagnosis: CLINICAL ... exam and imaging Treatment ... • Biologics: Anti-TNF
Myocarditis 

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic
Build clinical suspicion ... myocarditis Clinical ... Low voltage Treatment ... calcineurin inhibitor, anti-metabolite
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Clinical Manifestations ... Syndrome: • Anti-GAD ... Person Syndrome Treatment ... IVIG: Rituximab (anti-CD20 ... Diagnosis #Management #treatment
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Diagnosis: • Based on clinical ... - but 5% have anti—muscle-specific ... Treatment: • Symptomatic ... treatment Of ocular ... - Improves clinical