18 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... asthma, allergy, drug ... glucocorticoid treatment ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... , drug-dependent ... comparison #table #rheumatology ... #diagnosis #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... infection) - Drugs ... (Beta lactam antibiotics ... #differential # ... diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Drug Reaction with ... Severe adverse drug ... Exanthematous drug ... : Drug withdrawal ... #diagnosis #management
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... Erythematosus > 100 drugs ... associated with drug-induced ... #medications #drugs ... #diagnosis #rheumatology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
hypertension and/or drug ... Idiosyncratic drug ... Idiosyncratic drug ... #diagnosis #causes ... #hematology
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Important culprits: antibiotics ... immediately. ❼ Give drugs ... annotate notes/drug ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... anaphylaxis (→ 3-1) Drug ... #Hyperthermia #Differential ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
immune deficiency, Drugs ... , Unknown cause ... Treatment: • Etiological ... #management #treatment ... #summary #rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... , drug-dependent ... - Less common (drug-dependent ... DrugInduced #Lupus #DIL #rheumatology ... #diagnosis #treatment