228 results
Hashitoxicosis - Autoimmune thyroid disease overlap syndrome of Graves' and Hashimoto's disease

Autoimmune thyroid disease overlap syndrome
destruction by cell and antibody-mediated ... peroxidase (TPO) antibodies ... • TSH-receptor antibodies ... your balance of antibodies ... Endocrinology #Pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... history of the disease ... decline in maternal antibody ... or undetectable antibodies ... Agammaglobulinemia #XLinked #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Allergen-specific lgE antibodies ... - IgG or IgM antibody ... during hemolytic disease ... antigen - Antigen-antibody ... Classification #Pathophysiology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... sclerosis, NMOSD, MOG antibody ... glycoprotein (MOG) antibody ... MCTD - Bechet disease ... Antiamphiphysin antibodies
Nomenclature of Monoclonal Antibodies (-mab)

- Dr. Axel Grothey
@agrothey

#Nomenclature #Monoclonal #Antibodies #Mab #Antibody #Naming
of Monoclonal Antibodies ... Nomenclature #Monoclonal #Antibodies ... #Mab #Antibody
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear Antibody ... Antineutrophil cytoplasmic antibodies ... anti-topoisomerase antibody ... connective tissue disease ... Antineutrophil #antibodies
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... polyangiitis U1-RNP antibody ... Endomyseal antibody ... (TTG) - Celiac disease ... #rheumatology #antibodies
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
Tests for Celiac Disease ... patients with celiac disease ... Sensitivity for celiac disease ... anti-transglutaminase antibody ... value for celiac disease
Estimated Timeline for Detection of SARS-CoV-2 Infection Relative to Symptom Onset

#COVID19 #SARSCOV2 #PCR #Serology #Antibodies #Antibody
PCR #Serology #Antibodies ... #Antibody #Laboratory
COVID-19 PCR and Serology Testing - Timeline
 • Nucleic Acid Test - Most reliable and can
first 7 days • Antibody ... PCR #Serology #antibody ... #antibodies #testing