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diagnosis differential causes algorithm hematology management clinical pathophysiology symptoms nephrology neurology signs workup endocrinology treatment pharmacology physicalexam cardiology hemolytic iron
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Etiologies of Folate Deficiency ... have hemolytic anemia ... develop folate deficiency ... contraceptive and anticonvulsants ... functional folate deficiency
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... , GATA2 deficiency ... , CTLA4 deficiency ... - NSAIDs - Anticonvulsants
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... B12 or Folate deficiency ... Cell RBC: G6PD deficiency ... elliptocytosis, Severe iron deficiency
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... anemia, Thalassemia ... Thalassemia, Iron-deficiency ... Post-splenectomy, Vitamin E deficiency ... cells - G-6-PD deficiency
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Anemia - Underproduction ... Algorithm - Iron deficiency ... anemia - Anemia ... inflammation - Anemia ... and/or folate deficiency
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach to Anemia ... inflammation) • Iron deficiency ... Sideroblastic anemia ... Megaloblastic: Folate deficiency ... , B12 deficiency
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing SUMMARY: - RDW, FEP, serum iron,
Iron Deficiency ... Anemia vs Anemia ... TIBC-specific for iron deficiency ... Bloodman #Iron #Deficiency ... #Anemia #Chronic
Therapeutic Indications for the Anticonvulsant Agents #Anticonvulsant #Antiseizure #Medications #Pharmacology #Table #Neurology #Epilepsy #Management
Indications for the Anticonvulsant ... Agents #Anticonvulsant
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80 fL) • Iron Deficiency ... Poisoning • Anemia ... 100 fL) • B12 Deficiency ... • Folate Deficiency
Elliptocyte - Note the shape of these appropriately named erythrocytes. In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... and severe iron deficiency ... anemia.
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